MICROSCOPY:


AURORA

AIRY BEAM LIGHT SHEET MICROSCOPY IMAGING SYSTEM

  • Wide field of view - image larger specimens faster than other systems
  • Isotropic axial resolution - image samples from any angle
  • Low photo bleaching - image specimens for longer
  • Modular design - customisable system to suit your research needs
  • Intuitive operation – minimal training required
  • Programmable - Develop your own functions/code
  • Flexible specimen preparation – use live, fixed and cleared specimens (incubation and perfusion facilitated)

Aurora is an innovative, compact, flexible and affordable single and/or multiphoton light sheet fluorescence imaging system for rapid, large 3D volumetric imaging, high resolution, multicolour, time-lapse imaging and live cell imaging.

Airy beam Light Sheet Microscopy (ABLSM) is an increasingly popular imaging modality for visualising whole samples, such as embryos and organoids, and is used for the longtime observation of embryonal development in different model organisms in developmental biology, cell biology, neuroscience and regenerative medicine.

Aurora is already being used out in the field by many leading organisations with outstanding results.

DOWNLOADS

CORE FEATURES

The entry level Aurora system is a compact bench-top light system with a footprint of 60 x 60 x 30 cm and features:

  • Sub-cellular 1-micron isotropic resolution
  • Peak Irradiance of 80% less than a Gaussian light sheet, whilst maintaining a similar axial resolution
  • 20x larger X-Y field of view than a Gaussian light sheet
  • 500x faster than confocal microscopy
  • 10x increase in signal-to-noise after Airy deconvolution

The entry-level system can be easily adapted or upgraded for a multitude of applications. Additional modules include:

  • Wide range of continuous wave laser lines available
  • Multiphoton light sheet imaging configuration
  • Fully or partially automated stage
  • Environmental control

aurora custom development programme

  • Joining the Aurora customisation programme places the configuration and specifications of an instrument directly in your hands, so that your microsope meets the exacting needs of your research requirements. The benefits of the programme include:

  • PERSONALISED PROGRAMME

    Tailor the programme to suit your budget or timescales

  • DEVELOP A CUSTOM SYSTEM

    Choose from a range of modules and create a system to suit your research requirements

  • HANDS-ON-TRAINING

    Practical assistance to help you optimise sample imaging protocols

  • PRIORITY TECHNICAL SUPPORT

    Help from our dedicated application specialists and engineers

  • GRANT APPLICATION SUPPORT

    Access available funds with the support of our grant writing team

  • CO-AUTHORED PAPERS

    Develop papers in conjunction with us and/or other programme members

  • PREFERENTIAL PURCHASE TERMS

    Programme members receive preferential purchase terms

GET IN TOUCH WITH OUR LASER SPECIALISTS

IMAGE CREDITS

*1 “488nm excitation; auto fluorescence in plant root.”

Credit: Dr Stefan Sassmann University of Exeter, College of Life and Environmental Sciences, “488nm excitation; auto fluorescence in plant root.”

*2 “Cleared Mouse Brain thy1-GFP labeled actin 600x600x400 micron z-stack.”

Credit: Dr Anthony Vernon and Robert Chesters, Department of Basic and Clinical Neuroscience, Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry,
Psychology and Neuroscience; MRC Centre for Neurodevelopment Disorders, King’s College London.

*3 “Single Photon Image of clarified neurons thy1-GFP 200 microns deep”

Credit: Dr Anthony Vernon and Robert Chesters, Department of Basic and Clinical Neuroscience, Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry,
Psychology and Neuroscience; MRC Centre for Neurodevelopment Disorders, King’s College London.

*4 “Cleared brain 600x600x640 microns thy1-GFP Actin Fire coloured height map.”

Credit: Dr Anthony Vernon and Robert Chesters, Department of Basic and Clinical Neuroscience, Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry,
Psychology and Neuroscience; MRC Centre for Neurodevelopment Disorders, King’s College London.

*5 “GFP-expressing hCS Neurite.”

Credit: James Crowe and Deepak Srivastava, Institute of Psychiatry, Psychology & Neuroscience, King’s College London.

*6 “Multiphoton Image of Mouse Brain Flattened Overlay two colour Auto Fluorescence and GFP”

Dr Anthony Vernon and Robert Chesters, Department of Basic and Clinical Neuroscience, Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry,
Psychology and Neuroscience; MRC Centre for Neurodevelopment Disorders, King’s College London.

*7 “Live 2 day old zebrafish tail maximum projection, labelled with GFP-sox17-cyan, RFP-prox1-magenta.”

Credit: Prof. Lene Broeng Oddershede, Dr Younes Farangebarooji and Dr Elke Ober, Niels Bohr Institute Copenhagen.

LASER ENQUIRIES

+44 (0)141 945 0500

Head Office

 

+1-720-242-8190

USA, East Coast

 

+1-408-519-6016

USA, West Coast

MICROSCOPE ENQUIRIES

+44 (0)148 368 5170